Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845735 | 0.83 | GAA (0.40) | HTTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL9735234 | 0.80 | KMT2A (0.44) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL9876240 | 0.79 | KDM4E (0.38) | HTTALDH1A1PKMLMNAMAPT | |
| SCHEMBL9735952 | 0.75 | TSHR (0.50) | MEN1KMT2AALDH1A1PKMPOLB | |
| SCHEMBL9736879 | 0.74 | L3MBTL1 (0.44) | MEN1KMT2AALDH1A1LMNAATM | |
| SCHEMBL18164586 | 0.72 | MEN1 (0.71) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL9521448 | 0.72 | TSHR (0.46) | HTTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9736151 | 0.72 | LMNA (0.46) | MEN1KMT2AALDH1A1PKMPOLB | |
| SCHEMBL2958844 | 0.70 | THRB (0.66) | HTTMEN1KMT2AALDH1A1PKM | |
| SCHEMBL2955815 | 0.66 | PKM (0.63) | HTTMEN1KMT2AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173503-A | Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-22 | — | — | US | disclosed |
| EP-0432892-A1 | Imidazole fungicides | AgrEvo UK Limited (GB) | 1991-06-19 | — | — | EP | disclosed |