Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735952 | 0.79 | TSHR (0.50) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9736879 | 0.78 | L3MBTL1 (0.44) | LMNAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL27267123 | 0.75 | LMNA (0.53) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9735234 | 0.75 | KMT2A (0.44) | LMNAKMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL9876240 | 0.72 | KDM4E (0.38) | LMNAMAPTALDH1A1TSHRPKM | |
| SCHEMBL9736764 | 0.72 | HTT (0.41) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL9521448 | 0.68 | TSHR (0.46) | LMNAKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL2693466 | 0.67 | LMNA (0.81) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL23351448 | 0.65 | LMNA (0.60) | LMNAKMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL2693467 | 0.65 | LMNA (0.63) | LMNAKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173503-A | Derivatives of N,N-dimethyl-4-phenylalkylenesulfonyl-imidazole -1-sulphonamides; phytopathogenic fungi | SCHERING AGROCHEMICALS LIMITED (GB) | 1992-12-22 | — | — | US | disclosed |
| EP-0432892-A1 | Imidazole fungicides | AgrEvo UK Limited (GB) | 1991-06-19 | — | — | EP | disclosed |