Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735412 | 0.88 | ABCC9 (0.32) | ABCC9 | |
| SCHEMBL9735244 | 0.87 | LMNA (0.36) | ALDH1A1POLBTSHRABCC9SMN1; SMN2 | |
| SCHEMBL9738250 | 0.85 | OPRM1 (0.36) | TSHRABCC9SMN1; SMN2 | |
| SCHEMBL9734831 | 0.85 | ALOX5 (0.37) | IDO1ALDH1A1TSHRABCC9SMN1; SMN2 | |
| SCHEMBL9736167 | 0.85 | ABCC9 (0.37) | ALDH1A1ABCC9SMN1; SMN2 | |
| SCHEMBL8536595 | 0.85 | ABCC9 (0.49) | ABCC9 | |
| SCHEMBL9143340 | 0.85 | ABCC9 (0.45) | ALDH1A1TSHRABCC9 | |
| SCHEMBL9143344 | 0.85 | ABCC9 (0.45) | ALDH1A1TSHRABCC9 | |
| SCHEMBL9143349 | 0.85 | ABCC9 (0.45) | ALDH1A1TSHRABCC9 | |
| SCHEMBL9735276 | 0.83 | ABCC9 (0.32) | ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |
| EP-0415065-A1 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |