Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9735503 | 0.82 | ALOX5 (0.35) | MEN1KMT2ACASP3LMNAKDM4E | |
| SCHEMBL9736959 | 0.80 | KDM4E (0.33) | MEN1KMT2ACAPN9CASP3CYP3A4 | |
| SCHEMBL9735589 | 0.80 | CCNE1 (0.35) | MEN1KMT2ACAPN9CASP3CYP3A4 | |
| SCHEMBL9737016 | 0.78 | MALT1 (0.35) | MEN1KMT2ACAPN9CASP3CYP3A4 | |
| SCHEMBL9736241 | 0.74 | ALDH1A1 (0.35) | MEN1KMT2ACAPN9CASP3CYP3A4 | |
| SCHEMBL9732771 | 0.73 | MEN1 (0.34) | MEN1KMT2ACAPN9CASP3CYP3A4 | |
| SCHEMBL9735535 | 0.71 | KMT2A (0.36) | MEN1KMT2ALMNAARALDH1A1 | |
| SCHEMBL9736949 | 0.70 | MAPT (0.32) | MEN1KMT2ALMNANR3C1PGR | |
| SCHEMBL8316461 | 0.69 | L3MBTL1 (0.41) | MEN1KMT2ANR3C1PGRNR3C2 | |
| SCHEMBL8314877 | 0.69 | MEN1 (0.36) | MEN1KMT2ACYP3A4TDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |