Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737163 | 0.92 | ALDH1A1 (0.43) | L3MBTL1NPSR1TDP1KDM4EHPGD | |
| SCHEMBL9737606 | 0.90 | KDM4E (0.49) | L3MBTL1TDP1KDM4EMEN1KMT2A | |
| SCHEMBL9737699 | 0.84 | PTGDR2 (0.46) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL18116342 | 0.84 | HTR1B (0.44) | LMNA | |
| SCHEMBL9738747 | 0.83 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9737796 | 0.82 | GABRA2 (0.47) | — | |
| SCHEMBL9738233 | 0.82 | KCNQ3 (0.43) | L3MBTL1KDM4EHPGDALDH1A1MAPK1 | |
| SCHEMBL23013190 | 0.81 | EGFR (0.54) | L3MBTL1NPSR1KDM4EMEN1KMT2A | |
| SCHEMBL9737626 | 0.81 | KCNQ3 (0.45) | KDM4EHPGDALDH1A1 | |
| SCHEMBL9737283 | 0.80 | PTGDR2 (0.47) | KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |