Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737699 | 0.89 | PTGDR2 (0.46) | KCNQ3KCNQ2ALDH1A1APOBEC3AIRAK4 | |
| SCHEMBL9737491 | 0.89 | PTGS2 (0.41) | KCNQ3KCNQ2ALDH1A1IRAK4PTGS2 | |
| SCHEMBL9738192 | 0.89 | KDM4E (0.39) | ALDH1A1APOBEC3AIRAK4PTGS2KDM4E | |
| SCHEMBL9737626 | 0.84 | KCNQ3 (0.45) | KCNQ3KCNQ2ALDH1A1APOBEC3AIRAK4 | |
| SCHEMBL9738747 | 0.84 | ALDH1A1 (0.45) | KCNQ3KCNQ2ALDH1A1APOBEC3APTGS2 | |
| SCHEMBL18116342 | 0.82 | HTR1B (0.44) | — | |
| SCHEMBL9737130 | 0.82 | L3MBTL1 (0.48) | ALDH1A1KDM4EL3MBTL1MAPK1HPGD | |
| SCHEMBL9737796 | 0.80 | GABRA2 (0.47) | — | |
| SCHEMBL15210509 | 0.80 | POLB (0.48) | KCNQ3KCNQ2PARP1ALDH1A1APOBEC3A | |
| SCHEMBL9737634 | 0.80 | KDM4E (0.48) | ALDH1A1APOBEC3AKDM4EL3MBTL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |