Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737163 | 0.91 | ALDH1A1 (0.43) | KDM4ETDP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9737130 | 0.90 | L3MBTL1 (0.48) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL9737961 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KCNK3KCNK9 | |
| SCHEMBL9737634 | 0.84 | KDM4E (0.48) | KDM4EL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9737862 | 0.84 | TSPO (0.52) | LMNA | |
| SCHEMBL9737601 | 0.83 | KDM4E (0.50) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL9738192 | 0.83 | KDM4E (0.39) | KDM4ESMN1; SMN2ALDH1A1HPGDRAB9A | |
| SCHEMBL9738434 | 0.82 | KCNQ3 (0.41) | SMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL9737572 | 0.79 | TSPO (0.45) | KDM4EALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL9738542 | 0.78 | TSPO (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |