Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | AQP1 | P29972 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | PTGES | O14684 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795238 | 0.91 | ALDH1A1 (0.57) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL9738547 | 0.85 | CA2 (0.39) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL9738317 | 0.85 | KDM4E (0.52) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL9737828 | 0.85 | ALOX5 (0.40) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL574683 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL2741876 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL572711 | 0.79 | LMNA (0.62) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL15677231 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL2741882 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4EUSP2LMNAHPGD | |
| SCHEMBL9736354 | 0.79 | PTGES (0.36) | ALDH1A1KDM4EUSP2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2290843-A | — | — | None | — | — | JP | disclosed |
| US-5145867-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| JP-H02290843-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVE | HOECHST AG | 1990-11-30 | — | — | JP | disclosed |