Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738547 | 0.88 | CA2 (0.39) | ALOX5PTGESCA2ALDH1A1KDM4E | |
| SCHEMBL9736354 | 0.87 | PTGES (0.36) | ALOX5PTGESCA2ALDH1A1KDM4E | |
| SCHEMBL9737264 | 0.85 | ALDH1A1 (0.52) | ALOX5PTGESCA2ALDH1A1KDM4E | |
| SCHEMBL9736980 | 0.84 | CA2 (0.37) | CA2ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL573875 | 0.76 | CA2 (0.46) | ALOX5PTGESCA2ALDH1A1KDM4E | |
| SCHEMBL11787224 | 0.74 | NSD2 (0.44) | CA2ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL11795238 | 0.74 | ALDH1A1 (0.57) | ALOX5PTGESCA2ALDH1A1KDM4E | |
| SCHEMBL11784469 | 0.73 | NSD2 (0.42) | CA2ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL9739873 | 0.71 | KDM4E (0.36) | CA2ALDH1A1KDM4EUSP2LMNA | |
| SCHEMBL9737103 | 0.71 | CA2 (0.39) | CA2ALDH1A1KDM4EUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145867-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |