Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737606 | 0.83 | KDM4E (0.49) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL9737524 | 0.75 | TSPO (0.64) | — | |
| SCHEMBL9737163 | 0.74 | ALDH1A1 (0.43) | KDM4ETDP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9737130 | 0.73 | L3MBTL1 (0.48) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL11727532 | 0.72 | SLC2A2 (0.52) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL11242309 | 0.71 | SLC2A2 (0.51) | KDM4ETDP1L3MBTL1MEN1MAPT | |
| SCHEMBL9737961 | 0.68 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL11256580 | 0.67 | KDM4E (0.72) | KDM4EMEN1KMT2ASLC2A2ALDH1A1 | |
| SCHEMBL9737862 | 0.67 | TSPO (0.52) | LMNAPOLB | |
| SCHEMBL13172597 | 0.67 | MAPT (0.50) | KDM4ETDP1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | claimed |
| US-5114944-A | Anxiolytic and anticonvulsant agents; muscle relaxants | A. H. ROBINS COMPANY INCORPORATED (US) | 1992-05-19 | — | — | US | disclosed |