Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | LSS | P48449 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737428 | 0.89 | KCNH2 (0.59) | KCNH2GAABCHEACHELSS | |
| SCHEMBL9736462 | 0.88 | KCNH2 (0.58) | KCNH2KDM4EALDH1A1BCHEACHE | |
| SCHEMBL9736388 | 0.82 | CYSLTR1 (0.48) | CYSLTR2CYSLTR1GPBAR1ALOX5PDE10A | |
| SCHEMBL9737324 | 0.82 | ALDH1A1 (0.55) | KCNH2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL9733327 | 0.82 | ALDH1A1 (0.55) | KCNH2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL9736703 | 0.82 | ALDH1A1 (0.55) | KCNH2GAAKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9732991 | 0.81 | ALDH1A1 (0.54) | KCNH2GAAKDM4EALDH1A1LMNA | |
| SCHEMBL8810787 | 0.80 | KCNH2 (0.81) | KCNH2ALDH1A1ACHEDRD2DRD4 | |
| SCHEMBL2567854 | 0.80 | LMNA (0.69) | GAAKDM4EALDH1A1CYSLTR2CYSLTR1 | |
| SCHEMBL9733233 | 0.78 | CACNA1F (0.50) | KCNH2ACHECYSLTR2CYSLTR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |