Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738703 | 0.89 | CNR2 (0.38) | ALDH1A1SMN1; SMN2FGFR1NPC1RAB9A | |
| SCHEMBL9733560 | 0.87 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2F10NPC1RAB9A | |
| SCHEMBL8088434 | 0.86 | S100A4 (0.37) | S100A4KDM4EALDH1A1SMN1; SMN2NR1H2 | |
| SCHEMBL9733518 | 0.85 | FTO (0.31) | SMN1; SMN2 | |
| SCHEMBL9147909 | 0.85 | NR1H4 (0.33) | KDM4EF10 | |
| SCHEMBL9733395 | 0.83 | S100A4 (0.35) | S100A4KDM4ENR1H2NR1H3FGFR1 | |
| SCHEMBL9369702 | 0.82 | ABCC9 (0.35) | F10 | |
| SCHEMBL9732962 | 0.82 | MAPT (0.35) | S100A4ALDH1A1SMN1; SMN2NR1H2NR1H3 | |
| SCHEMBL9734520 | 0.81 | — | — | |
| SCHEMBL8076894 | 0.77 | KMT2A (0.36) | KDM4EALDH1A1NR1H2NR1H3F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |