Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 2/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9737735 | 0.87 | S100A4 (0.35) | ALDH1A1SMN1; SMN2NPC1RAB9AF10 | |
| SCHEMBL8084222 | 0.87 | ALDH1A1 (0.41) | ALDH1A1MAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9734520 | 0.86 | — | — | |
| SCHEMBL9733518 | 0.82 | FTO (0.31) | SMN1; SMN2FTO | |
| SCHEMBL9147909 | 0.82 | NR1H4 (0.33) | MAPTF10NPSR1 | |
| SCHEMBL9738703 | 0.82 | CNR2 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9732962 | 0.80 | MAPT (0.35) | ALDH1A1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL9369702 | 0.80 | ABCC9 (0.35) | F10CYP1A2CYP2C19LMNA | |
| SCHEMBL8085176 | 0.77 | MAOA (0.42) | ALDH1A1MAOAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9372808 | 0.76 | NPC1 (0.41) | ALDH1A1MAOAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |