Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736980 | 0.86 | CA2 (0.37) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9736354 | 0.85 | PTGES (0.36) | KDM4EALDH1A1HPGDMAPTCA2 | |
| SCHEMBL9737103 | 0.82 | CA2 (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9738317 | 0.78 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9739881 | 0.73 | SCN1A (0.40) | KDM4EALDH1A1CA2CA9CA4 | |
| SCHEMBL9736362 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL9737828 | 0.71 | ALOX5 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL11160672 | 0.71 | PKM (0.33) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL11192732 | 0.69 | KDM4E (0.59) | KDM4EALDH1A1HPGDMAPTCA2 | |
| SCHEMBL11165688 | 0.68 | CISD1 (0.49) | KDM4EALDH1A1HPGDSCN9ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145867-A | NAPHTHYLALKYLAMINO-SUBSTITUTED SULFAMOYLBENZOIC ACID DERIVATIVES, AND THE USE THEREOF AS MEDICINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |