Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740084 | 0.81 | CNR2 (0.36) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9735503 | 0.81 | ALOX5 (0.35) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9736448 | 0.81 | ALOX5 (0.35) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9733368 | 0.80 | ALOX5 (0.36) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9736109 | 0.79 | CNR2 (0.35) | ALOX5RAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9736085 | 0.72 | IDO1 (0.34) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9734818 | 0.71 | ALOX5 (0.36) | ALOX5RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL9735313 | 0.70 | ALOX5 (0.32) | ALOX5RAB9AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9732736 | 0.70 | KDM4E (0.33) | RAB9AKDM4EALDH1A1NPC1LMNA | |
| SCHEMBL9737143 | 0.69 | ALDH1A1 (0.36) | RAB9AKDM4EALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |