Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TLK2 | Q86UE8 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733368 | 0.90 | ALOX5 (0.36) | KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9733370 | 0.85 | KDM4E (0.34) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9737456 | 0.84 | ALDH1A1 (0.34) | KDM4ENPC1RAB9ATLK2ALDH1A1 | |
| SCHEMBL9732791 | 0.79 | TLK2 (0.34) | KDM4ETLK2ALDH1A1S100A4 | |
| SCHEMBL9740084 | 0.75 | CNR2 (0.36) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9735940 | 0.70 | KDM4E (0.34) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9737906 | 0.70 | ALOX5 (0.35) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9733395 | 0.67 | S100A4 (0.35) | KDM4ENPC1RAB9AS100A4 | |
| SCHEMBL9735503 | 0.65 | ALOX5 (0.35) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9733242 | 0.65 | ALDH1A1 (0.39) | NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143924-A | OXODIHYDROPYRIDYL CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-09-01 | — | — | US | disclosed |