Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | IL18 | Q14116 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238812 | 0.87 | SMPD1 (0.50) | MAPTMEN1KMT2AALDH1A1TAS1R3 | |
| SCHEMBL8669187 | 0.86 | KMT2A (0.47) | MAPTMEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL7604101 | 0.83 | RAB9A (0.57) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7604198 | 0.83 | TAS1R3 (0.78) | MAPTMEN1KMT2AALDH1A1TAS1R3 | |
| SCHEMBL10608014 | 0.82 | MAOA (0.51) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL7605886 | 0.81 | KMT2A (0.59) | MAPTMEN1KMT2AALDH1A1LMNA | |
| Diflubenzuron SCHEMBL42416 | 0.81 | RAB9A (0.59) | MAPTMEN1KMT2AALDH1A1HTT | |
| SCHEMBL11244486 | 0.81 | RAB9A (0.55) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL10703352 | 0.81 | KMT2A (0.53) | MAPTMEN1KMT2ALMNAHTT | |
| Diflubenzuron SCHEMBL18837607 | 0.81 | RAB9A (0.59) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193249-A2 | Benzoyl urea derivatives having ati-tumor activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-09-03 | — | — | EP | claimed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | claimed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| EP-0107214-A2 | Pharmaceutical compositions containing benzoyl-phenyl ureas with anti-tumour activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-05-02 | — | — | EP | disclosed |