Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739705 | 0.86 | MEN1 (0.37) | SLC6A3POLBMEN1KMT2ANPC1 | |
| SCHEMBL9739485 | 0.82 | CYP1A2 (0.37) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL9739775 | 0.82 | NPC1 (0.38) | POLBNPC1HTTSMN1; SMN2 | |
| SCHEMBL9740491 | 0.81 | MEN1 (0.40) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL9740046 | 0.81 | NPC1 (0.37) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL9740266 | 0.81 | SLC22A12 (0.38) | POLBMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9739157 | 0.81 | PARP1 (0.39) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL9740469 | 0.80 | GAA (0.43) | POLBMEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL9738757 | 0.80 | NPC1 (0.43) | POLBMEN1KMT2ANPC1HTT | |
| SCHEMBL9738947 | 0.80 | HTT (0.42) | POLBSLC6A4MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |