Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740491 | 0.84 | MEN1 (0.40) | HTTSMN1; SMN2PGRMEN1KMT2A | |
| SCHEMBL9739008 | 0.83 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2PGRMEN1KMT2A | |
| SCHEMBL9738757 | 0.82 | NPC1 (0.43) | HTTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9742164 | 0.82 | CHRM5 (0.47) | HTTSMN1; SMN2PGRMEN1KMT2A | |
| SCHEMBL9739249 | 0.80 | SLC6A3 (0.40) | HTTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9740279 | 0.80 | HTT (0.47) | HTTSMN1; SMN2PGRMEN1KMT2A | |
| SCHEMBL9739810 | 0.79 | PARP1 (0.47) | NPC1POLBOPRK1OPRM1NPY5R | |
| SCHEMBL9738938 | 0.79 | NPC1 (0.40) | HTTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9738986 | 0.77 | RXFP1 (0.42) | HTTSMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL9738615 | 0.77 | CHRM5 (0.46) | HTTSMN1; SMN2PGRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |