Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 4/20 | 0.34 |
| ▸ | CCND1 | P24385 | 4/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739249 | 0.81 | SLC6A3 (0.40) | PARP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9740469 | 0.80 | GAA (0.43) | NPC1POLBKDM4EPRKCASMN1; SMN2 | |
| SCHEMBL9199100 | 0.79 | PARP1 (0.36) | PARP1NPC1POLBIMPDH2IMPDH1 | |
| SCHEMBL9739775 | 0.79 | NPC1 (0.38) | NPC1POLBHTTSMN1; SMN2ADRB1 | |
| SCHEMBL9740491 | 0.76 | MEN1 (0.40) | NPC1POLBALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9739705 | 0.76 | MEN1 (0.37) | PARP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9740046 | 0.76 | NPC1 (0.37) | PARP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9738947 | 0.75 | HTT (0.42) | NPC1POLBHTTSMN1; SMN2KMT2A | |
| SCHEMBL9738757 | 0.75 | NPC1 (0.43) | PARP1NPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL9739485 | 0.75 | CYP1A2 (0.37) | NPC1POLBKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |