Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739485 | 0.94 | CYP1A2 (0.37) | SLC22A12NPC1MAPTRAB9ATP53 | |
| SCHEMBL9739249 | 0.81 | SLC6A3 (0.40) | NPC1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL9738592 | 0.77 | HSD11B1 (0.41) | NPC1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9740491 | 0.76 | MEN1 (0.40) | NPC1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL9200324 | 0.76 | NPC1 (0.38) | NPC1MAPTRAB9ATP53PTK2B | |
| SCHEMBL9738986 | 0.76 | RXFP1 (0.42) | NPC1SMN1; SMN2POLBMEN1KMT2A | |
| SCHEMBL9740469 | 0.75 | GAA (0.43) | NPC1MAPTRAB9ATP53SMN1; SMN2 | |
| SCHEMBL9738947 | 0.75 | HTT (0.42) | NPC1RAB9ASMN1; SMN2POLBMEN1 | |
| SCHEMBL9738757 | 0.75 | NPC1 (0.43) | NPC1MAPTSMN1; SMN2POLBMEN1 | |
| SCHEMBL9213340 | 0.75 | NPC1 (0.36) | NPC1MAPTRAB9ATP53PTK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |