Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740266 | 0.94 | SLC22A12 (0.38) | MAPTSMN1; SMN2MEN1ALDH1A1KMT2A | |
| SCHEMBL9739249 | 0.82 | SLC6A3 (0.40) | MAPTSMN1; SMN2MEN1HTTKMT2A | |
| SCHEMBL9738592 | 0.79 | HSD11B1 (0.41) | SMN1; SMN2MEN1HTTKMT2ANPC1 | |
| SCHEMBL9701851 | 0.78 | TSHR (0.37) | CYP1A2P2RX7TSHRCYP3A4NFKB1 | |
| SCHEMBL9739775 | 0.76 | NPC1 (0.38) | SMN1; SMN2HTTCCNCCDK8NPC1 | |
| SCHEMBL9740491 | 0.75 | MEN1 (0.40) | CYP1A2CYP3A4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9739705 | 0.75 | MEN1 (0.37) | CYP1A2MAPTSMN1; SMN2MEN1HTT | |
| SCHEMBL9739157 | 0.75 | PARP1 (0.39) | MAPTSMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL9738986 | 0.75 | RXFP1 (0.42) | CYP1A2TSHRCYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL9740469 | 0.74 | GAA (0.43) | MAPTSMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016529-A1 | NOVEL ISOINDOLE DERIVATIVES AND MEDICAMENTS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1992-10-01 | — | — | WO | disclosed |