Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740178 | 0.97 | HRH3 (0.48) | POLBMAPTHRH3LTA4HSPHK1 | |
| SCHEMBL9740308 | 0.91 | KDM4E (0.51) | HRH3SPHK1MAOAMAOBALDH1A1 | |
| SCHEMBL9740276 | 0.85 | HTR1A (0.52) | MAPTHRH3SPHK1MEN1ALDH1A1 | |
| SCHEMBL9739334 | 0.83 | TRPV6 (0.59) | POLBHRH3FKBP1AALDH1A1 | |
| SCHEMBL9741170 | 0.81 | FAAH (0.52) | LTA4HSPHK1ADRA1AADRA1B | |
| SCHEMBL9739552 | 0.80 | CHRNB2 (0.57) | POLBMAPTHRH3HRH1HRH2 | |
| SCHEMBL9208504 | 0.80 | HRH2 (0.49) | POLBMAPTHRH3LTA4HHRH1 | |
| SCHEMBL7247932 | 0.75 | LTA4H (0.67) | HRH3LTA4H | |
| SCHEMBL7249465 | 0.73 | CHRNB4 (0.49) | HRH3LTA4HMAOBHRH1HRH2 | |
| SCHEMBL9739220 | 0.73 | HRH3 (0.52) | POLBMAPTHRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |