Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 9/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ARNT | P27540 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741306 | 0.83 | ATM (0.47) | L3MBTL1SMN1; SMN2ALDH1A1HTTPDE7A | |
| SCHEMBL9711235 | 0.77 | PDE7A (0.38) | SMN1; SMN2ALDH1A1PDE7ATDP1LMNA | |
| SCHEMBL9739624 | 0.75 | LMNA (0.46) | L3MBTL1SMN1; SMN2ALDH1A1PDE7ATDP1 | |
| SCHEMBL27562903 | 0.73 | KDM4E (0.38) | L3MBTL1SMN1; SMN2ATMTDP1KDM4E | |
| SCHEMBL6602067 | 0.72 | KDM4E (0.35) | L3MBTL1SMN1; SMN2ALDH1A1HTTATM | |
| SCHEMBL7819980 | 0.71 | KDM4E (0.42) | ALDH1A1KDM4ELDHACYP1A2CYP2C19 | |
| SCHEMBL24377922 | 0.70 | KDM4E (0.36) | L3MBTL1SMN1; SMN2ATMKDM4ELDHA | |
| SCHEMBL3018147 | 0.70 | ALDH1A1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1HTTATM | |
| SCHEMBL1255217 | 0.69 | ATM (0.39) | L3MBTL1SMN1; SMN2ALDH1A1PDE7AATM | |
| SCHEMBL28941715 | 0.69 | ATM (0.50) | L3MBTL1PDE7AATMKDM4ELDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |