Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | USP10 | Q14694 | 1/20 | 0.41 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739474 | 0.83 | L3MBTL1 (0.37) | ATMTDP1PDE7ACA2ALDH1A1 | |
| SCHEMBL9740256 | 0.78 | SMN1; SMN2 (0.40) | TDP1PDE7AALDH1A1MEN1KMT2A | |
| SCHEMBL9711187 | 0.71 | FBP1 (0.41) | ATMTDP1HSPB1ALDH1A1MEN1 | |
| SCHEMBL779536 | 0.71 | DDR1 (0.38) | CA2ALDH1A1CES2CES1PTGS2 | |
| SCHEMBL29722933 | 0.71 | DDR1 (0.38) | CA2ALDH1A1CES2CES1PTGS2 | |
| SCHEMBL29391079 | 0.70 | CES2 (0.35) | ATMTDP1USP7USP10USP47 | |
| SCHEMBL21450904 | 0.69 | RIPK2 (0.52) | ALDH1A1MEN1KMT2AMCL1CES2 | |
| SCHEMBL9711276 | 0.68 | KDM4E (0.39) | ATMTDP1CA2ALDH1A1KMT2A | |
| SCHEMBL29722960 | 0.68 | ALDH1A1 (0.35) | ATMTDP1CA2ALDH1A1CES2 | |
| SCHEMBL775820 | 0.68 | ALDH1A1 (0.35) | ATMTDP1CA2ALDH1A1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |