Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.45 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738870 | 0.84 | APLNR (0.42) | IDO1CA2 | |
| SCHEMBL9740073 | 0.80 | TUBB4A (0.51) | CALM1HTR2CCA2ALDH1A1 | |
| SCHEMBL9739054 | 0.75 | IDO1 (0.44) | IDO1SNCALTA4HCHEK2TAAR1 | |
| SCHEMBL5365772 | 0.73 | PTPRC (0.47) | ARKDM4EALDH1A1 | |
| SCHEMBL22800044 | 0.73 | CA2 (0.52) | IDO1LTA4HTAAR1CA2CHRM2 | |
| SCHEMBL1923230 | 0.71 | HTR1D (0.39) | ALDH1A1 | |
| SCHEMBL25798810 | 0.70 | PDE10A (0.59) | LTA4HCALM1 | |
| SCHEMBL28704684 | 0.69 | MAPK1 (0.47) | IDO1LTA4HCHEK2ARKDM4E | |
| SCHEMBL14243461 | 0.69 | CALM1 (0.59) | TAAR1CALM1ARCA2KDM4E | |
| SCHEMBL28711054 | 0.69 | ALDH1A1 (0.56) | IDO1LTA4HTAAR1CALM1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |