Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739252 | 0.95 | KMT2A (0.42) | KMT2AMEN1ALDH1A1RAB9APOLB | |
| SCHEMBL9740712 | 0.84 | SIGMAR1 (0.42) | DRD4 | |
| SCHEMBL9216372 | 0.79 | MEN1 (0.42) | KMT2ADRD4MEN1ALDH1A1 | |
| SCHEMBL9739714 | 0.78 | MEN1 (0.38) | KMT2ADRD4MEN1RAB9APKM | |
| SCHEMBL9215338 | 0.75 | MEN1 (0.41) | KMT2ADRD4MEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL9204551 | 0.73 | ADRA1B (0.41) | ALDH1A1 | |
| SCHEMBL9208157 | 0.73 | MEN1 (0.37) | KMT2AMEN1RAB9A | |
| SCHEMBL9205094 | 0.72 | KDM4E (0.40) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL19859652 | 0.72 | CYP2D6 (0.41) | DRD4ALDH1A1 | |
| SCHEMBL19859651 | 0.72 | CYP2D6 (0.41) | DRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |