Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213470 | 0.74 | LMNA (0.37) | CYP24A1SIGMAR1TUBB4ATUBBTUBA3C | |
| SCHEMBL9740712 | 0.71 | SIGMAR1 (0.42) | IDH1SIGMAR1 | |
| SCHEMBL9207731 | 0.71 | SIGMAR1 (0.43) | CYP24A1SIGMAR1 | |
| SCHEMBL14577547 | 0.66 | CYP2D6 (0.52) | LMNAMAPTALDH1A1KMT2A | |
| SCHEMBL16232221 | 0.65 | MTNR1A (0.56) | MTNR1BNQO2MTNR1A | |
| SCHEMBL4225647 | 0.64 | CYP19A1 (0.47) | ALDH1A1 | |
| SCHEMBL28242912 | 0.64 | CYP1A2 (0.58) | LMNAPKMHTTSMN1; SMN2TDP1 | |
| SCHEMBL9630809 | 0.64 | CYP19A1 (0.52) | MTNR1BSIGMAR1MTNR1A | |
| SCHEMBL7296513 | 0.64 | CYP19A1 (0.52) | SIGMAR1 | |
| SCHEMBL3021792 | 0.64 | CYP2D6 (0.44) | LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |