Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD5 | P21918 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204729 | 0.80 | KDM2B (0.43) | SLC6A4HTR1AABCB1CA12CA1 | |
| SCHEMBL9738921 | 0.79 | HTR1A (0.48) | SLC6A4HTR1ASIGMAR1ABCB1LMNA | |
| SCHEMBL8540875 | 0.77 | HTR6 (0.54) | DRD2HTR6LMNASMN1; SMN2DRD4 | |
| SCHEMBL8540877 | 0.77 | HTR6 (0.54) | DRD2HTR6LMNASMN1; SMN2DRD4 | |
| SCHEMBL9207731 | 0.76 | SIGMAR1 (0.43) | HTR1ASIGMAR1DRD4HRH1ACHE | |
| SCHEMBL9208592 | 0.74 | HTR1A (0.50) | SLC6A4HTR1ASIGMAR1KCNA3 | |
| SCHEMBL9739469 | 0.74 | ABCB1 (0.55) | SLC6A4HTR1ASIGMAR1ABCB1HTT | |
| SCHEMBL5966607 | 0.74 | CA12 (0.47) | SLC6A4SIGMAR1LMNAPKMHTT | |
| SCHEMBL19859670 | 0.74 | CYP2D6 (0.53) | DRD2HTR2APKMHTTDRD1 | |
| SCHEMBL29571633 | 0.74 | CYP2D6 (0.53) | DRD2HTR2APKMHTTDRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |