⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739830 | 0.85 | FAAH (0.30) | — | |
| SCHEMBL9736590 | 0.78 | NPSR1 (0.35) | — | |
| SCHEMBL9736381 | 0.78 | NPSR1 (0.35) | — | |
| SCHEMBL10378727 | 0.78 | NPSR1 (0.35) | — | |
| SCHEMBL9738881 | 0.73 | LMNA (0.36) | — | |
| SCHEMBL9740476 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL10378318 | 0.71 | NPSR1 (0.35) | — | |
| SCHEMBL9736469 | 0.71 | NPSR1 (0.35) | — | |
| SCHEMBL9740806 | 0.69 | TMEM97 (0.33) | — | |
| SCHEMBL6639842 | 0.65 | CA2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5138050-A | 6-amido-1-methyl carbapenems | MERCK & CO., INC. (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1990000170-A1 | NOVEL 6-AMIDO-1-METHYLCARBAPENEMS | MERCK & CO., INC. (US) | 1990-01-11 | — | — | WO | disclosed |