SCHEMBL9740565

SCHEMBL9740565

CCOCCNC(O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.50
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.41
RAB9A P51151 2/20 0.40
POLB P06746 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
HTT P42858 2/20 0.39
MTOR P42345 1/20 0.38
GRM7 Q14831 1/20 0.38
EPHX2 P34913 1/20 0.38
MMP8 P22894 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14288495 0.82 RAB9A (0.61) SMN1; SMN2ALDH1A1KDM4ELMNARAB9A
SCHEMBL9729078 0.82 ALDH1A1 (0.47) SMN1; SMN2ALDH1A1KDM4ELMNARAB9A
SCHEMBL29650956 0.79 MTOR (0.58) SMN1; SMN2ALDH1A1KDM4ELMNARAB9A
SCHEMBL10823219 0.76 MEN1 (0.45) SMN1; SMN2ALDH1A1KDM4ELMNARAB9A
SCHEMBL6202712 0.75 SMN1; SMN2 (0.49) SMN1; SMN2ALDH1A1KDM4ELMNAMEN1
SCHEMBL11590155 0.75 MTOR (0.48) SMN1; SMN2ALDH1A1KDM4ELMNARAB9A
SCHEMBL6435556 0.72 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1KDM4ERAB9AHTT
SCHEMBL8570275 0.72 HRH1 (0.45) KDM4ELMNARAB9ATAAR1MTOR
SCHEMBL9729471 0.71 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1KDM4ERAB9AHTT
SCHEMBL11745430 0.70 HRH1 (0.47) SMN1; SMN2ALDH1A1LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5091403-A SULFINYL IMIDAZOLE DERIVATIVES AND ANTIULCER AGENTS CONTAINING THE SAME NIPPON CHEMIPHAR CO., LTD. (JP) 1992-02-25 US disclosed