Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14288495 | 0.78 | RAB9A (0.61) | MEN1KMT2ACYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9740565 | 0.76 | SMN1; SMN2 (0.50) | MEN1KMT2ACYP3A4HTTSMN1; SMN2 | |
| SCHEMBL9729078 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11211010 | 0.69 | HDAC3 (0.48) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL6202712 | 0.69 | SMN1; SMN2 (0.49) | MEN1KMT2ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL11113439 | 0.68 | LMNA (0.52) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL11211662 | 0.67 | SIGMAR1 (0.48) | MEN1KMT2ACYP1A2CYP3A4GAA | |
| SCHEMBL11745430 | 0.66 | HRH1 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8793685 | 0.66 | SIGMAR1 (0.46) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6435556 | 0.66 | SMN1; SMN2 (0.71) | CYP3A4CYP2D6CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61106543-A | — | — | None | — | — | JP | disclosed |
| JP-S61106543-A | N-SUBSTITUTED AMINE | TOKUYAMA SODA CO LTD | 1986-05-24 | — | — | JP | disclosed |