SCHEMBL974150

SCHEMBL974150

CCOc1cc(C(O)C(=O)O)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.69
BLM P54132 1/20 0.69
NPSR1 Q6W5P4 1/20 0.69
GAA P10253 4/20 0.51
ALDH1A1 P00352 2/20 0.51
MAPT P10636 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TOP2A P11388 1/20 0.48
TP53 P04637 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ALPI P09923 1/20 0.45
ALPG P10696 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BCHE P06276 2/20 0.44
TYR P14679 2/20 0.44
ACHE P22303 2/20 0.44
CYP3A4 P08684 1/20 0.43
MGAM O43451 1/20 0.43
AKR1C3 P42330 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350145 1.00 TSHR (0.69) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL974152 1.00 TSHR (0.69) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL30112581 1.00 TSHR (0.69) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL28441888 0.98 TSHR (0.68) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL28441886 0.98 TSHR (0.68) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL11137471 0.88 TSHR (0.66) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL8339848 0.88 TSHR (0.66) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL31151753 0.87 TSHR (0.64) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL11138285 0.87 TSHR (0.64) TSHRBLMNPSR1GAAALDH1A1
SCHEMBL11138289 0.87 TSHR (0.64) TSHRBLMNPSR1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745779-B Method for preparing 3-ethoxy-4-hydroxy mandelic acid at low temperature 重庆欣欣向荣精细化工股份有限公司 2025-02-25 CN claimed
CN-115745779-A Method for preparing 3-ethoxy-4-hydroxymandelic acid at low temperature 重庆欣欣向荣精细化工有限公司 2023-03-07 CN claimed
US-20230022284-A1 AN ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES RHODIA OPERATIONS (FR) 2023-01-26 US claimed
CN-111848377-B Preparation method of ethyl vanillin 重庆化工职业学院 2022-12-06 CN claimed
US-11484052-B2 Vanillin and/or ethylvanillin, process for their preparations and use thereof RHODIA OPERATIONS (FR) 2022-11-01 US claimed
EP-4065543-A1 ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES RHODIA OPERATIONS (FR) 2022-10-05 EP claimed
CN-114746581-A Electrochemical process for the preparation of vanillin or derivatives thereof 罗地亚经营管理公司 2022-07-12 CN claimed
WO-2021102613-A1 ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES RHODIA OPERATIONS (FR) 2021-06-03 WO claimed
US-20210120854-A1 NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2021-04-29 US claimed
EP-3658525-A1 NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF Rhodia Operations (FR) 2020-06-03 EP claimed
EP-2222627-B3 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF RHODIA OPERATIONS (FR) 2015-04-08 EP claimed
US-8759573-B2 Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof RHODIA OPERATIONS (FR) 2014-06-24 US claimed
US-8431750-B2 Preparation of hydroxyaromatic aldehydes RHODIA OPERATIONS (FR) 2013-04-30 US claimed
EP-2300403-B1 METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM RHODIA OPERATIONS (FR) 2013-01-23 EP claimed
EP-2222627-B1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF RHODIA OPERATIONS (FR) 2012-08-08 EP claimed
US-20110306802-A1 PREPARATION OF HYDROXYAROMATIC ALDEHYDES SPECIALTY OPERATIONS FRANCE (FR) 2011-12-15 US claimed
US-20110009664-A1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF Rhodia Pperations (FR) 2011-01-13 US claimed
US-6753441-B1 CONDENSING, IN WATER AND BASE, HYDROXYLATED AROMATIC COMPOUND WITH GLYOXYLIC ACID USING POLYCARBOXYLIC ACID CATALYST RHODIA CHIMIE (FR) 2004-06-22 US claimed
EP-1087924-B1 METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS OPTIONALLY SUBSTITUTED RHODIA CHIMIE SA (FR) 2004-02-25 EP claimed
EP-0578550-B1 Process for the para-hydroxyalkylation of hydroxylated aromatic compounds RHONE POULENC CHIMIE (FR) 1996-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210120854-A1 NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF COMT, VARS1, BPGM TSHR 4860/4885BLM 3970/4885NPSR1 4655/4885
US-20110009664-A1 METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF HPD, COMT, PAH TSHR 4522/4885BLM 1275/4885NPSR1 384/4885
US-20230022284-A1 AN ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES VRK1, COMT, VRK2 TSHR 4775/4885BLM 2613/4885NPSR1 3653/4885
US-20110306802-A1 PREPARATION OF HYDROXYAROMATIC ALDEHYDES AOX1, ALDH2, ALDH1A1 TSHR 4450/4885BLM 1541/4885NPSR1 3112/4885
US-11484052-B2 Vanillin and/or ethylvanillin, process for their preparations and use thereof COMT, VARS1, BPGM TSHR 4859/4885BLM 3942/4885NPSR1 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.