Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350145 | 1.00 | TSHR (0.69) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL974150 | 1.00 | TSHR (0.69) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL30112581 | 1.00 | TSHR (0.69) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL28441888 | 0.98 | TSHR (0.68) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL28441886 | 0.98 | TSHR (0.68) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL11137471 | 0.88 | TSHR (0.66) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL8339848 | 0.88 | TSHR (0.66) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL31151753 | 0.87 | TSHR (0.64) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL11138285 | 0.87 | TSHR (0.64) | TSHRBLMNPSR1GAAALDH1A1 | |
| SCHEMBL11138289 | 0.87 | TSHR (0.64) | TSHRBLMNPSR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745779-B | Method for preparing 3-ethoxy-4-hydroxy mandelic acid at low temperature | 重庆欣欣向荣精细化工股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-115745779-A | Method for preparing 3-ethoxy-4-hydroxymandelic acid at low temperature | 重庆欣欣向荣精细化工有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-20230022284-A1 | AN ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES | RHODIA OPERATIONS (FR) | 2023-01-26 | — | — | US | claimed |
| EP-4065543-A1 | ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES | RHODIA OPERATIONS (FR) | 2022-10-05 | — | — | EP | claimed |
| CN-114746581-A | Electrochemical process for the preparation of vanillin or derivatives thereof | 罗地亚经营管理公司 | 2022-07-12 | — | — | CN | claimed |
| WO-2021102613-A1 | ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES | RHODIA OPERATIONS (FR) | 2021-06-03 | — | — | WO | claimed |
| CN-106029627-B | Method for isolating mandelic compounds in salified form and use thereof for preparing aromatic aldehydes | 罗地亚经营管理公司 | 2020-02-28 | — | — | CN | claimed |
| EP-3083547-B1 | METHOD FOR SEPARATING MANDELIC COMPOUNDS IN SALIFIED FORM AND USE OF SAME FOR PREPARING AROMATIC ALDEHYDE | RHODIA OPERATIONS (FR) | 2018-09-05 | — | — | EP | claimed |
| US-9567283-B2 | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | RHODIA OPERATIONS (FR) | 2017-02-14 | — | — | US | claimed |
| US-20160318839-A1 | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | RHODIA OPERATIONS (FR) | 2016-11-03 | — | — | US | claimed |
| US-9006496-B2 | Method of separating phenolic compounds in salified form | RHODIA OPERATIONS (FR) | 2015-04-14 | — | — | US | claimed |
| EP-2222627-B3 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | RHODIA OPERATIONS (FR) | 2015-04-08 | — | — | EP | claimed |
| US-8759573-B2 | Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof | RHODIA OPERATIONS (FR) | 2014-06-24 | — | — | US | claimed |
| US-8431750-B2 | Preparation of hydroxyaromatic aldehydes | RHODIA OPERATIONS (FR) | 2013-04-30 | — | — | US | claimed |
| EP-2300403-B1 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM | RHODIA OPERATIONS (FR) | 2013-01-23 | — | — | EP | claimed |
| EP-2222627-B1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | RHODIA OPERATIONS (FR) | 2012-08-08 | — | — | EP | claimed |
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | SPECIALTY OPERATIONS FRANCE (FR) | 2011-12-15 | — | — | US | claimed |
| US-20110009664-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | Rhodia Pperations (FR) | 2011-01-13 | — | — | US | claimed |
| US-6753441-B1 | CONDENSING, IN WATER AND BASE, HYDROXYLATED AROMATIC COMPOUND WITH GLYOXYLIC ACID USING POLYCARBOXYLIC ACID CATALYST | RHODIA CHIMIE (FR) | 2004-06-22 | — | — | US | claimed |
| CN-115745779-B | Method for preparing 3-ethoxy-4-hydroxy mandelic acid at low temperature | 重庆欣欣向荣精细化工股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-115745779-B | Method for preparing 3-ethoxy-4-hydroxy mandelic acid at low temperature | 重庆欣欣向荣精细化工股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-115745779-B | Method for preparing 3-ethoxy-4-hydroxy mandelic acid at low temperature | 重庆欣欣向荣精细化工股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-118726997-A | Electrooxidation preparation method of vanillin and analogues thereof | 厦门大学 | 2024-10-01 | — | — | CN | disclosed |
| CN-117964464-A | Synthesis method of ethyl vanillin | 浙江师范大学 | 2024-05-03 | — | — | CN | disclosed |
| CN-117800831-A | Synthesis method of 3-methoxy-4-hydroxy mandelic acid | 山东泓瑞医药科技股份公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115745779-A | Method for preparing 3-ethoxy-4-hydroxymandelic acid at low temperature | 重庆欣欣向荣精细化工有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115745779-A | Method for preparing 3-ethoxy-4-hydroxymandelic acid at low temperature | 重庆欣欣向荣精细化工有限公司 | 2023-03-07 | — | — | CN | disclosed |
| CN-115745779-A | Method for preparing 3-ethoxy-4-hydroxymandelic acid at low temperature | 重庆欣欣向荣精细化工有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-20230022284-A1 | AN ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES | RHODIA OPERATIONS (FR) | 2023-01-26 | — | — | US | disclosed |
| CN-111848377-B | Preparation method of ethyl vanillin | 重庆化工职业学院 | 2022-12-06 | — | — | CN | disclosed |
| US-11484052-B2 | Vanillin and/or ethylvanillin, process for their preparations and use thereof | RHODIA OPERATIONS (FR) | 2022-11-01 | — | — | US | disclosed |
| CN-114746581-A | Electrochemical process for the preparation of vanillin or derivatives thereof | 罗地亚经营管理公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-113896369-A | Method for treating phenolic wastewater in production process of ethyl vanillin | 重庆欣欣向荣精细化工有限公司 | 2022-01-07 | — | — | CN | disclosed |
| US-20210120854-A1 | NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | SPECIALTY OPERATIONS FRANCE (FR) | 2021-04-29 | — | — | US | disclosed |
| EP-3658525-A1 | NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | Rhodia Operations (FR) | 2020-06-03 | — | — | EP | disclosed |
| CN-110944969-A | Novel vanillin and/or ethyl vanillin, method for the production thereof and use thereof | 罗地亚经营管理公司 | 2020-03-31 | — | — | CN | disclosed |
| CN-106029627-B | Method for isolating mandelic compounds in salified form and use thereof for preparing aromatic aldehydes | 罗地亚经营管理公司 | 2020-02-28 | — | — | CN | disclosed |
| US-10544081-B2 | Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds | RHODIA OPERATIONS (FR) | 2020-01-28 | — | — | US | disclosed |
| US-20190031588-A1 | NEW VANILLIN AND OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | SPECIALTY OPERATIONS FRANCE (FR) | 2019-01-31 | — | — | US | disclosed |
| WO-2019020773-A1 | NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | RHODIA OPERATIONS (FR) | 2019-01-31 | — | — | WO | disclosed |
| US-20170183283-A1 | METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS IN STIRRED REACTORS | RHODIA OPERATIONS (FR) | 2017-06-29 | — | — | US | disclosed |
| US-9567283-B2 | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | RHODIA OPERATIONS (FR) | 2017-02-14 | — | — | US | disclosed |
| US-20160318839-A1 | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | RHODIA OPERATIONS (FR) | 2016-11-03 | — | — | US | disclosed |
| US-20160297735-A1 | Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds | RHODIA OPERATIONS (FR) | 2016-10-13 | — | — | US | disclosed |
| CN-105862070-A | Method for preparing 3-methoxy-4-hydroxymandelic acid or 3-ethoxyl-4-hydroxymandelic acid through bipolar membrane electrodialysis | 广州大有精细化工厂 | 2016-08-17 | — | — | CN | disclosed |
| CN-105862070-A | Method for preparing 3-methoxy-4-hydroxymandelic acid or 3-ethoxyl-4-hydroxymandelic acid through bipolar membrane electrodialysis | 广州大有精细化工厂 | 2016-08-17 | — | — | CN | disclosed |
| US-9403745-B2 | Method for separating salified phenolic compounds | RHODIA OPERATIONS (FR) | 2016-08-02 | — | — | US | disclosed |
| US-20150274625-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | SPECIALTY OPERATIONS FRANCE (FR) | 2015-10-01 | — | — | US | disclosed |
| US-9079842-B2 | Method for separating salified phenolic compounds | RHODIA OPERATIONS (FR) | 2015-07-14 | — | — | US | disclosed |
| US-9006496-B2 | Method of separating phenolic compounds in salified form | RHODIA OPERATIONS (FR) | 2015-04-14 | — | — | US | disclosed |
| CN-102634544-B | Biosynthesis method of ethyl vanillin | UNIV JIANGNAN | 2015-01-07 | — | — | CN | disclosed |
| US-8759573-B2 | Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof | RHODIA OPERATIONS (FR) | 2014-06-24 | — | — | US | disclosed |
| US-8431750-B2 | Preparation of hydroxyaromatic aldehydes | RHODIA OPERATIONS (FR) | 2013-04-30 | — | — | US | disclosed |
| US-20120264982-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | RHODIA OPERATIONS (FR) | 2012-10-18 | — | — | US | disclosed |
| CN-102634544-A | Biosynthesis method of ethyl vanillin | UNIV JIANGNAN | 2012-08-15 | — | — | CN | disclosed |
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | SPECIALTY OPERATIONS FRANCE (FR) | 2011-12-15 | — | — | US | disclosed |
| US-20110230674-A1 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM | RHODIA OPERATIONS (FR) | 2011-09-22 | — | — | US | disclosed |
| CN-102190580-A | Preparation method of 3-ethoxy-4-hydroxymandelic acid used as intermediate for synthesizing ethyl vanillin | CHONGQING THRIVE CHEMICAK CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-102190580-A | Preparation method of 3-ethoxy-4-hydroxymandelic acid used as intermediate for synthesizing ethyl vanillin | CHONGQING THRIVE CHEMICAK CO LTD | 2011-09-21 | — | — | CN | disclosed |
| US-20110009664-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | Rhodia Pperations (FR) | 2011-01-13 | — | — | US | disclosed |
| CN-100526281-C | Method of synthesizing 3-methoxy-4-dydroxymandelic acid or 3-ethoxy-4-dydroxymandelic acid by acetaldehyde acid method | JIHUA GROUP CO LTD (CN) | 2009-08-12 | — | — | CN | disclosed |
| CN-101012161-A | Method of synthesizing 3-methoxy-4-dydroxymandelic acid or 3-ethoxy-4-dydroxymandelic acid by acetaldehyde acid method | JIHUA GROUP CO LTD (CN) | 2007-08-08 | — | — | CN | disclosed |
| US-4401830-A | Process for preparation of 3-alkoxy-4-hydroxyphenylacetic acid | UBE INDUSTRIES, LTD. (JP) | 1983-08-30 | — | — | US | disclosed |
| US-4339602-A | Process of preparation of racemic hydroxyarylglycolic acids and novel products resulting therefrom | SOCIETE FRANCAISE HOECHST (FR) | 1982-07-13 | — | — | US | disclosed |
| US-4339594-A | HYDROGENATION, HYDROGENATION CATALYSTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-07-13 | — | — | US | disclosed |
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |
| US-4218380-A | OXIDATION OF THE A-HYDROXY-ARYLACETIC ACID | BAYER AKTIENGESELLSCHAFT (DE) | 1980-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10544081-B2 | Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds | PAH, DDC, GRHPR | TSHR 4868/4885BLM 2803/4885NPSR1 3298/4885 |
| US-20210120854-A1 | NEW VANILLIN AND/OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | COMT, VARS1, BPGM | TSHR 4860/4885BLM 3970/4885NPSR1 4655/4885 |
| US-20170183283-A1 | METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS IN STIRRED REACTORS | COMT, PAH, HPD | TSHR 3985/4885BLM 2303/4885NPSR1 346/4885 |
| US-20150274625-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | COMT, GRHPR, ME1 | TSHR 4778/4885BLM 1155/4885NPSR1 1994/4885 |
| US-20110009664-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | HPD, COMT, PAH | TSHR 4522/4885BLM 1275/4885NPSR1 384/4885 |
| US-20230022284-A1 | AN ELECTROCHEMICAL METHOD FOR PREPARING VANILLIN OR ITS DERIVATIVES | VRK1, COMT, VRK2 | TSHR 4775/4885BLM 2613/4885NPSR1 3653/4885 |
| US-20110306802-A1 | PREPARATION OF HYDROXYAROMATIC ALDEHYDES | AOX1, ALDH2, ALDH1A1 | TSHR 4450/4885BLM 1541/4885NPSR1 3112/4885 |
| US-20160297735-A1 | Process for preparing mandelic aromatic compounds and aromatic aldehyde compounds | PAH, DDC, GRHPR | TSHR 4868/4885BLM 2803/4885NPSR1 3298/4885 |
| US-20110230674-A1 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM | REN, GRHPR, COMT | TSHR 4537/4885BLM 1231/4885NPSR1 1816/4885 |
| US-20160318839-A1 | Method for separating mandelic compounds in salified form and use of same for preparing aromatic aldehyde | COMT, DDC, GRHPR | TSHR 4862/4885BLM 1953/4885NPSR1 3712/4885 |
| US-20120264982-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | COMT, GRHPR, ME1 | TSHR 4778/4885BLM 1155/4885NPSR1 1994/4885 |
| US-11484052-B2 | Vanillin and/or ethylvanillin, process for their preparations and use thereof | COMT, VARS1, BPGM | TSHR 4859/4885BLM 3942/4885NPSR1 4639/4885 |
| US-20190031588-A1 | NEW VANILLIN AND OR ETHYLVANILLIN, PROCESS FOR THEIR PREPARATIONS AND USE THEREOF | VARS1, COMT, BPGM | TSHR 4858/4885BLM 4091/4885NPSR1 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.