Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | GYS1 | P13807 | 4/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9743185 | 0.82 | LMNA (0.47) | RNASEH1TYRERN1ALDH1A1GAA | |
| SCHEMBL25898933 | 0.79 | PTGS1 (0.57) | RNASEH1TYRERN1ALDH1A1GAA | |
| SCHEMBL17707900 | 0.79 | TYR (0.50) | RNASEH1TYRERN1ALDH1A1GAA | |
| SCHEMBL9742695 | 0.78 | RXRA (0.51) | RNASEH1TYRALDH1A1GAAALOX12 | |
| SCHEMBL7435559 | 0.78 | TRPA1 (0.55) | RNASEH1TYRERN1ALDH1A1GAA | |
| Isobutane SCHEMBL27537403 | 0.78 | BACE1 (0.48) | ALDH1A1GAAALOX12GYS1MEN1 | |
| SCHEMBL2870997 | 0.77 | ALOX15 (0.47) | ALDH1A1ALOX12GYS1PIK3CAMEN1 | |
| SCHEMBL8647267 | 0.76 | GYS1 (0.59) | GAAGYS1PIK3CA | |
| SCHEMBL14252297 | 0.76 | TYR (0.48) | RNASEH1TYRERN1ALDH1A1GAA | |
| SCHEMBL27436464 | 0.74 | TYR (0.43) | RNASEH1TYRERN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087548-A | POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION | JAPAN SYNTHETIC RUBBER CO., INC. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0227487-A2 | Positive type radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |