Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324702 | 0.81 | PTGS1 (0.57) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL27506947 | 0.74 | HPGD (0.48) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL20856035 | 0.73 | HPGD (0.53) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL31182212 | 0.72 | GABRA1 (0.58) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL282835 | 0.72 | GABRA1 (0.58) | HPGDALOX15CES2GALR3CYP1A2 | |
| Formaldehyde SCHEMBL27866505 | 0.72 | GABRA1 (0.52) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL28175280 | 0.72 | ALDH1A1 (0.52) | HPGDALOX15KMT2AMEN1POLB | |
| SCHEMBL487951 | 0.71 | LMNA (0.43) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL2984801 | 0.71 | ALOX15 (0.48) | HPGDALOX15CES2GALR3CYP1A2 | |
| SCHEMBL29462882 | 0.71 | HPGD (0.69) | HPGDCYP1A2CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274467-B1 | HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM | GEHO, W., Blair (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0274467-A1 | HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM. | BLAIR GEHO W (US) | 1988-07-20 | — | — | EP | disclosed |
| EP-0274467-A4 | HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM. | BLAIR GEHO W (US) | 1988-06-16 | — | — | EP | disclosed |
| WO-1988000474-A1 | HEPATOCYTE DIRECTED VESICLE DELIVERY SYSTEM | BLAIR GEHO W (US) | 1988-01-28 | — | — | WO | disclosed |