SCHEMBL9745359

SCHEMBL9745359

CCc1cccc([SiH2]O)c1CC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.46
GABRB2 P47870 4/20 0.46
TAAR1 Q96RJ0 2/20 0.39
HTR1A P08908 1/20 0.36
ANPEP P15144 2/20 0.33
DPP4 P27487 2/20 0.33
KCNH2 Q12809 1/20 0.33
SCN5A Q14524 1/20 0.33
DAO P14920 3/20 0.33
HTT P42858 1/20 0.32
CLCN2 P51788 1/20 0.32
DDO Q99489 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2522716 0.86 GABRA1 (0.42) GABRA1GABRB2TAAR1HTR1ADAO
SCHEMBL2519258 0.83 GABRA1 (0.48) GABRA1GABRB2ANPEPHTT
SCHEMBL2518240 0.83 CYP3A4 (0.40) GABRA1GABRB2
SCHEMBL6114437 0.80 GABRA1 (0.46) GABRA1GABRB2CLCN2MAOA
SCHEMBL2522784 0.79 GABRA1 (0.46) GABRA1GABRB2ANPEPDPP4DAO
SCHEMBL706449 0.79 GABRA1 (0.46) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL21383327 0.79 GABRA1 (0.41) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL704995 0.79 GABRA1 (0.41) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL703208 0.79 GABRA1 (0.41) GABRA1GABRB2TAAR1HTR1AKCNH2
SCHEMBL245773 0.77 GABRA1 (0.57) GABRA1GABRB2TAAR1HTR1AKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117705961-A Method for measuring hydroxyl content in low-viscosity hydroxyl silicone oil by utilizing soil sweeping and trapping principle 湖北兴瑞硅材料有限公司 2024-03-15 CN claimed
CN-113831732-B Low-water-absorption high-toughness high-temperature nylon composite material and preparation method thereof 浙江工业大学 2022-07-22 CN claimed
CN-113831732-A Low-water-absorption high-toughness high-temperature nylon composite material and preparation method thereof 浙江工业大学 2021-12-24 CN claimed
CN-117705961-A Method for measuring hydroxyl content in low-viscosity hydroxyl silicone oil by utilizing soil sweeping and trapping principle 湖北兴瑞硅材料有限公司 2024-03-15 CN disclosed
CN-113831732-B Low-water-absorption high-toughness high-temperature nylon composite material and preparation method thereof 浙江工业大学 2022-07-22 CN disclosed
CN-113831732-A Low-water-absorption high-toughness high-temperature nylon composite material and preparation method thereof 浙江工业大学 2021-12-24 CN disclosed
EP-2855018-B1 PROCESS OF PREPARATION OF A CATALYST COMPRISING A GROUP VIII METAL AND SILICON AND PROCESS OF SELECTIVE HYDROGENATION USING THAT CATALYST IFP ENERGIES NOW (FR) 2017-10-18 EP disclosed
US-9695095-B2 Process for preparing a catalyst based on a group VIII metal and containing silicon, and a process of selective hydrogenation implementing said catalyst IFP Energies Nouvelles (FR) 2017-07-04 US disclosed
US-20150141718-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON, AND A PROCESS OF SELECTIVE HYDROGENATION IMPLEMENTING SAID CATALYST IFP Energies Nouvelles (FR) 2015-05-21 US disclosed
EP-2855018-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON AND SELECTIVE HYDROGENATION PROCESS USING SAID CATALYST IFP Energies nouvelles (FR) 2015-04-08 EP disclosed
WO-2013175085-A1 PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON AND SELECTIVE HYDROGENATION PROCESS USING SAID CATALYST IFP Energies Nouvelles (FR) 2013-11-28 WO disclosed
US-5100762-A Radiation-sensitive polymer and radiation-sensitive composition containing the same MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed