SCHEMBL9745875

SCHEMBL9745875

CCC(c1ccccc1)[Si](O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.52
POLB P06746 1/20 0.47
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HKDC1 Q2TB90 1/20 0.41
TRPA1 O75762 1/20 0.41
AOC3 Q16853 1/20 0.40
NOS3 P29474 1/20 0.40
NOS2 P35228 1/20 0.40
HSD17B10 Q99714 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SIGMAR1 Q99720 1/20 0.38
MIF P14174 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GAA P10253 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22283489 0.77 LMNA (0.46) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL3794550 0.77 LMNA (0.46) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL5002935 0.77 LMNA (0.42) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL4494436 0.76 LMNA (0.45) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL523287 0.76 LMNA (0.45) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL2822248 0.74 LMNA (0.43) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL9716583 0.74 LMNA (0.43) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL12999580 0.72 LMNA (0.42) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL20658076 0.72 LMNA (0.42) LMNAPOLBMEN1KMT2AHKDC1
SCHEMBL9716576 0.72 LMNA (0.42) LMNAPOLBMEN1KMT2AHKDC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5099006-A ompounds for use in paints, for waterproofing, as adhesion promoters, mordants, sizing agents and intermediates RHONE-POULENC INC. (US) 1992-03-24 US disclosed
EP-0319384-A2 Cerium hydrocarbonsilyloxydes and process for their manufacture RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed
EP-0319383-A2 Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides RHONE-POULENC CHIMIE (FR) 1989-06-07 EP disclosed