SCHEMBL4494436

SCHEMBL4494436

CCC(c1ccccc1)[Si](C)(C)[O]

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.45
POLB P06746 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
MIF P14174 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HKDC1 Q2TB90 1/20 0.36
TRPA1 O75762 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22283489 0.84 LMNA (0.46) LMNAPOLBMEN1KMT2AHSD17B10
SCHEMBL523287 0.78 LMNA (0.45) LMNAPOLBMEN1KMT2ATSHR
SCHEMBL4058170 0.78 LMNA (0.41) LMNAPOLBMEN1KMT2AHSD17B10
SCHEMBL3794550 0.76 LMNA (0.46) LMNAPOLBMEN1KMT2AHSD17B10
SCHEMBL9745875 0.76 LMNA (0.52) LMNAPOLBMEN1KMT2AHSD17B10
SCHEMBL9716576 0.75 LMNA (0.42) LMNAPOLBMEN1KMT2ATSHR
SCHEMBL12999580 0.75 LMNA (0.42) LMNAPOLBMEN1KMT2ATSHR
SCHEMBL661362 0.74 LMNA (0.41) LMNAPOLBMEN1KMT2ATSHR
SCHEMBL9716567 0.74 LMNA (0.41) LMNAPOLBMEN1KMT2AALDH1A1
SCHEMBL2822248 0.72 LMNA (0.43) LMNAPOLBMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863875-B1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MAT INC (DE) 2009-12-09 EP claimed
JP-2008537967-A 2008-10-02 JP claimed
EP-1863875-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF Momentive Performance Materials GmbH (DE) 2007-12-12 EP claimed
WO-2006100098-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2006-09-28 WO claimed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
US-20160333171-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-17 US disclosed
EP-3093303-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2016-11-16 EP disclosed
EP-1863875-B1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MAT INC (DE) 2009-12-09 EP disclosed
EP-1863875-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF Momentive Performance Materials GmbH (DE) 2007-12-12 EP disclosed
WO-2006100098-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2006-09-28 WO disclosed
US-4070313-A PHENOLIC RESOLE, BLOWING AGENT, POLYSILOXANE UNION CARBIDE CORPORATION (US) 1978-01-24 US disclosed