Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747632 | 0.80 | LMNA (0.45) | ALDH1A1KDM4EMEN1GRM6GLA | |
| SCHEMBL3684218 | 0.78 | GRIA1 (0.49) | ALDH1A1NPC1KDM4EGRIN2DGRIN3B | |
| SCHEMBL9747366 | 0.77 | BRD4 (0.40) | ALDH1A1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9747279 | 0.70 | MAPT (0.49) | ALDH1A1KDM4EMEN1GRM6GLA | |
| SCHEMBL9747233 | 0.69 | MAPT (0.51) | ALDH1A1MEN1MAPTHPGDGRIK1 | |
| SCHEMBL9747070 | 0.68 | ALDH1A1 (0.42) | ALDH1A1NPC1GAAHTTMEN1 | |
| SCHEMBL9747658 | 0.64 | IMPDH2 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9746587 | 0.64 | ALDH1A1 (0.54) | ALDH1A1NPC1KDM4EMEN1GLA | |
| SCHEMBL9746859 | 0.64 | GRIA1 (0.47) | ALDH1A1KDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL9747395 | 0.64 | KMT2A (0.47) | ALDH1A1NPC1GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |