Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9747632 | 0.85 | LMNA (0.45) | BRD4TAS2R14KDM4EALDH1A1MEN1 | |
| SCHEMBL9747703 | 0.77 | ALDH1A1 (0.41) | BRD4TAS2R14PARP1KDM4EALDH1A1 | |
| SCHEMBL2194658 | 0.77 | TAS2R14 (0.61) | TAS2R14PARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL9747279 | 0.74 | MAPT (0.49) | TAS2R14KDM4EALDH1A1MEN1GRM6 | |
| SCHEMBL29460062 | 0.72 | F11 (0.58) | MEN1MAPTTHRBKMT2ARXFP1 | |
| SCHEMBL3223011 | 0.72 | F11 (0.58) | MEN1MAPTTHRBKMT2ARXFP1 | |
| SCHEMBL14722076 | 0.72 | BRD4 (0.53) | BRD4TAS2R14PARP1KDM4EALDH1A1 | |
| SCHEMBL17824995 | 0.72 | PARG (0.58) | BRD4TAS2R14KDM4EMAPTRXFP1 | |
| SCHEMBL4714760 | 0.72 | RXFP1 (0.42) | BRD4TAS2R14PARP1KDM4EMAPT | |
| SCHEMBL9747658 | 0.71 | IMPDH2 (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511152-A2 | Quinoxaline compounds, their preparation and use | NOVO NORDISK A/S (DK) | 1992-10-28 | — | — | EP | disclosed |