Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | PGK2 | P07205 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386026 | 0.84 | TACR1 (0.40) | ALDH1A1SMN1; SMN2CA2POLBNR3C1 | |
| SCHEMBL2259568 | 0.80 | ACHE (0.50) | POLBNR3C1ACHE | |
| SCHEMBL5161078 | 0.78 | ALDH1A1 (0.38) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| SCHEMBL9748234 | 0.78 | NR3C1 (0.37) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| SCHEMBL16673269 | 0.78 | ESR1 (0.44) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| SCHEMBL295944 | 0.77 | ESR1 (0.44) | ALDH1A1SMN1; SMN2NR3C1TSHRMEN1 | |
| SCHEMBL9632606 | 0.77 | NR3C1 (0.36) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| Tert-Butanol SCHEMBL9346954 | 0.76 | ALDH1A1 (0.53) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| SCHEMBL16673539 | 0.76 | ESR1 (0.42) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 | |
| SCHEMBL563683 | 0.76 | SLC6A2 (0.54) | ALDH1A1PGK1PGK2SMN1; SMN2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217159-B1 | ALDEHYDES, ACETALS, ALCOHOLS AND ETHERS WITH 3-METHYL OR 3,5-DIMETHYLBENZYL GROUPS, THEIR PREPARATION AND THEIR USE AS FRAGRANCE COMPOUNDS | Consortium für elektrochemische Industrie GmbH (DE) | 1992-01-02 | — | — | EP | claimed |
| US-9643946-B2 | Tricyclic compound and use thereof | SK CHEMICALS CO., LTD. (KR) | 2017-05-09 | — | — | US | disclosed |
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | SK CHEMICALS CO., LTD. (KR) | 2016-01-14 | — | — | US | disclosed |
| CN-101817800-A | Novel medicaments for the treatment of chronic obstructive pulmonary diseases | BOEHRINGER INGELHEIM PHARMA | 2010-09-01 | — | — | CN | disclosed |
| CN-101735166-A | Novel medicaments for the treatment of chronic obstructive pulmonary diseases | BOEHRINGER INGELHEIM PHARMA | 2010-06-16 | — | — | CN | disclosed |
| CN-101056640-A | Aerosol formulation for the inhalation of beta-agonists | BOEHRINGER INGELHEIM INT (DE) | 2007-10-17 | — | — | CN | disclosed |
| CN-1946406-A | Benzoxazines for treating respiratory diseases | BOEHRINGER INGELHEIM INT (DE) | 2007-04-11 | — | — | CN | disclosed |
| CN-1713914-A | Novel drug for treating chronic obstructive pulmonary disease | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-12-28 | — | — | CN | disclosed |
| EP-0217159-B1 | ALDEHYDES, ACETALS, ALCOHOLS AND ETHERS WITH 3-METHYL OR 3,5-DIMETHYLBENZYL GROUPS, THEIR PREPARATION AND THEIR USE AS FRAGRANCE COMPOUNDS | Consortium für elektrochemische Industrie GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4710316-A | Aldehydes, acetals, alcohols and ethers having 3-methyl- or 3,5-dimethyl-benzyl groups, their manufacture and perfume materials containing same | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1987-12-01 | — | — | US | disclosed |
| EP-0217159-A2 | Aldehydes, acetals, alcohols and ethers with 3-methyl or 3,5-dimethylbenzyl groups, their preparation and their use as fragrance compounds | Consortium für elektrochemische Industrie GmbH (DE) | 1987-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | GPR65, GPR119, GPR35 | ALDH1A1 2066/4885PGK1 1908/4885PGK2 2618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.