SCHEMBL974797

SCHEMBL974797

[O]Cc1c2ccccc2cc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
HSD17B10 Q99714 5/20 0.46
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C19 P33261 2/20 0.46
KDM4E B2RXH2 2/20 0.46
GLA P06280 2/20 0.46
HPGD P15428 2/20 0.46
CYP3A4 P08684 1/20 0.45
GPR35 Q9HC97 2/20 0.44
POLB P06746 1/20 0.44
HIF1A Q16665 1/20 0.44
CYP1B1 Q16678 1/20 0.44
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16414524 0.81 HTR2A (0.56) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL4647954 0.80 HTR2A (0.60) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL9445712 0.79 HTR2A (0.65) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL23527427 0.79 HTR2A (0.65) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL16414454 0.78 HTR2A (0.52) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL23259245 0.76 HTR2A (0.56) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL15351102 0.76 HTR2A (0.50) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL118514 0.75 HTR2A (0.60) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL1169916 0.75 HTR2A (0.60) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2
SCHEMBL22288196 0.75 HTR2A (0.60) HTR2AL3MBTL1HSD17B10ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107148453-B Photocurable composition 思美定株式会社 2021-08-17 CN disclosed
EP-3020715-B1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2021-06-16 EP disclosed
EP-3081612-B1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO LTD (JP) 2018-11-14 EP disclosed
US-9888688-B2 Tetrazolinone compounds and applications thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-02-13 US disclosed
US-9718999-B2 Photocurable composition having adhesive properties CEMEDINE CO., LTD (JP) 2017-08-01 US disclosed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-20160312089-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES CEMEDINE CO., LTD. (JP) 2016-10-27 US disclosed
EP-3081612-A1 PHOTOCURABLE COMPOSITION HAVING ADHESIVE PROPERTIES Cemedine Co., Ltd. (JP) 2016-10-19 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-06-02 US disclosed
WO-2006086325-A2 SYNTHESIS OF HOMOPOLYMERS AND BLOCK COPOLYMERS INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2006-08-17 WO disclosed
US-20060172914-A1 Synthesis of hybrid block copolymers and uses thereof INTEZYNE TECHNOLOGIES, INC. 2006-08-03 US disclosed
WO-2006074202-A2 SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2006-07-13 WO disclosed
US-20060142506-A1 Heterobifunctional poly(ethylene glycol) and uses thereof INTEZYNE TECHNOLOGIES, INC. 2006-06-29 US disclosed
WO-2006047419-A2 HETEROBIFUNCTIONAL POLY(ETHYLENE GLYCOL) AND USES THEREOF INTEZYNE TECHNOLOGIES, INCORPORATED (US) 2006-05-04 WO disclosed
US-7012147-B2 Enzyme inhibitors; chemical intermediates SANKYO COMPANY, LIMITED (JP) 2006-03-14 US disclosed
US-20060014965-A1 Indoline derivative and process for producing the same SANKYO COMPANY, LIMITED (JP) 2006-01-19 US disclosed
US-20040058979-A1 Indoline derivative and process for producing the same SANKYO COMPANY, LIMITED (JP) 2004-03-25 US disclosed
EP-1364942-A1 INDOLINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME Sankyo Company, Limited (JP) 2003-11-26 EP disclosed
CN-1036654-C Amide derivatives of antibiotic A 40926 LEPETIT SPA (IT) 1997-12-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142506-A1 Heterobifunctional poly(ethylene glycol) and uses thereof GNE, ALG1, EPHX2 HTR2A 4756/4885L3MBTL1 2653/4885HSD17B10 1804/4885
US-20160150787-A1 TETRAZOLINONE COMPOUNDS AND APPLICATIONS THEREOF SOD1, UQCRB, MT-CO1 HTR2A 3354/4885L3MBTL1 380/4885HSD17B10 1347/4885
US-20060014965-A1 Indoline derivative and process for producing the same ACAT2, ACAT1, INMT HTR2A 1094/4885L3MBTL1 3326/4885HSD17B10 300/4885
US-20040058979-A1 Indoline derivative and process for producing the same ACAT2, ACAT1, INMT HTR2A 1094/4885L3MBTL1 3326/4885HSD17B10 300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.