SCHEMBL9751038

SCHEMBL9751038

Cc1c(N)ccc(C2C=CCC2)c1N

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
TSHR P16473 1/20 0.34
PIK3CA P42336 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10477482 0.71 CHRNB2 (0.33) CYP3A4
SCHEMBL10582966 0.71 NR4A1 (0.42)
SCHEMBL9819199 0.71 CYP3A4 (0.39) CYP3A4TSHRPIK3CA
SCHEMBL10399467 0.71 CYP3A4 (0.35) CYP3A4
SCHEMBL9751041 0.70 CYP3A4 (0.35) CYP3A4TSHR
SCHEMBL9627029 0.70 CD44 (0.37)
SCHEMBL8292041 0.69 NOS3 (0.37)
SCHEMBL6755825 0.69 TRPA1 (0.39)
SCHEMBL9750929 0.68
SCHEMBL10582753 0.68 ALDH1A1 (0.40) CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5072045-A Polymerization inhibition using inert organic solvent AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-12-10 US disclosed
US-4985159-A Alkenylated toluenediamines as antioxidants for organic materials AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-01-15 US disclosed
US-4845291-A ANTIOXIDATNS, CHAIN EXTENDERS FOR POLYURETHANES AND/OR POLYUREAS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-07-04 US disclosed
US-4794194-A Alkenylated toluenediisocyanates for use in preparing polyurethane urea systems AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-12-27 US disclosed
EP-0272650-A1 Diamino-beta-alkylstyrenes for use in preparing polyurethane/urea systems AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-06-29 EP disclosed
US-4714778-A Alkenylated toluenediamines for use in preparing polyurethane/urea systems AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-12-22 US disclosed
EP-0235825-A2 Alkenylated toluenediamines for use in preparing polyurethane/urea systems AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-09-09 EP disclosed