Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.60 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.60 |
| ▸ | ABAT | P80404 | 1/20 | 0.60 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.60 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TOP2A | P11388 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4288561 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Ethyl Vanillin SCHEMBL29351334 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Ethyl Vanillin SCHEMBL719058 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Ethyl Vanillin SCHEMBL30247 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL1121580 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| SCHEMBL7034558 | 0.81 | FDPS (0.71) | ALDH1A1HPGDTDP1KDM4ERAB9A | |
| SCHEMBL30262368 | 0.81 | FDPS (0.71) | ALDH1A1HPGDTDP1KDM4ERAB9A | |
| SCHEMBL31009650 | 0.81 | ALDH1A1 (0.66) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Ethyl Vanillin SCHEMBL30402049 | 0.80 | ALDH1A1 (0.97) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 | |
| Ethyl Vanillin SCHEMBL5277489 | 0.80 | ALDH1A1 (0.97) | ALDH1A1HPGDTDP1TRIM24ALDH5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087924-B1 | METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS OPTIONALLY SUBSTITUTED | RHODIA CHIMIE SA (FR) | 2004-02-25 | — | — | EP | claimed |
| EP-0709361-B1 | Process for the preparation of isovanilline | RHODIA CHIMIE SA (FR) | 1999-02-03 | — | — | EP | claimed |
| US-5786516-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1998-07-28 | — | — | US | claimed |
| US-5648552-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1997-07-15 | — | — | US | claimed |
| EP-0709361-A1 | Process for the preparation of isovanilline | RHONE-POULENC CHIMIE (FR) | 1996-05-01 | — | — | EP | claimed |
| US-20170183283-A1 | METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS IN STIRRED REACTORS | RHODIA OPERATIONS (FR) | 2017-06-29 | — | — | US | disclosed |
| US-9403745-B2 | Method for separating salified phenolic compounds | RHODIA OPERATIONS (FR) | 2016-08-02 | — | — | US | disclosed |
| US-20150274625-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | SPECIALTY OPERATIONS FRANCE (FR) | 2015-10-01 | — | — | US | disclosed |
| US-9079842-B2 | Method for separating salified phenolic compounds | RHODIA OPERATIONS (FR) | 2015-07-14 | — | — | US | disclosed |
| US-9006496-B2 | Method of separating phenolic compounds in salified form | RHODIA OPERATIONS (FR) | 2015-04-14 | — | — | US | disclosed |
| US-8759573-B2 | Method for preparing optionally substituted p-hydroxymandelic compounds and derivatives thereof | RHODIA OPERATIONS (FR) | 2014-06-24 | — | — | US | disclosed |
| US-20120264982-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | RHODIA OPERATIONS (FR) | 2012-10-18 | — | — | US | disclosed |
| US-20110230674-A1 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM | RHODIA OPERATIONS (FR) | 2011-09-22 | — | — | US | disclosed |
| US-20110009664-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | Rhodia Pperations (FR) | 2011-01-13 | — | — | US | disclosed |
| US-6753441-B1 | CONDENSING, IN WATER AND BASE, HYDROXYLATED AROMATIC COMPOUND WITH GLYOXYLIC ACID USING POLYCARBOXYLIC ACID CATALYST | RHODIA CHIMIE (FR) | 2004-06-22 | — | — | US | disclosed |
| EP-0709361-B1 | Process for the preparation of isovanilline | RHODIA CHIMIE SA (FR) | 1999-02-03 | — | — | EP | disclosed |
| US-5786516-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1998-07-28 | — | — | US | disclosed |
| US-5648552-A | Process for the preparation of isovanillin | RHONE-POULENC CHIMIE (FR) | 1997-07-15 | — | — | US | disclosed |
| EP-0709361-A1 | Process for the preparation of isovanilline | RHONE-POULENC CHIMIE (FR) | 1996-05-01 | — | — | EP | disclosed |
| US-5430183-A | Para-hydroxyalkylation of hydroxylated aromatic compounds | RHONE-POULENC CHIMIE (FR) | 1995-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183283-A1 | METHOD FOR PREPARING P-HYDROXYMANDELIC COMPOUNDS IN STIRRED REACTORS | COMT, PAH, HPD | ALDH1A1 245/4885HPGD 145/4885TDP1 1937/4885 |
| US-20150274625-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | COMT, GRHPR, ME1 | ALDH1A1 776/4885HPGD 315/4885TDP1 2750/4885 |
| US-20110009664-A1 | METHOD FOR PREPARING OPTIONALLY SUBSTITUTED P-HYDROXYMANDELIC COMPOUNDS AND DERIVATIVES THEREOF | HPD, COMT, PAH | ALDH1A1 1106/4885HPGD 86/4885TDP1 1578/4885 |
| US-20110230674-A1 | METHOD OF SEPARATING PHENOLIC COMPOUNDS IN SALIFIED FORM | REN, GRHPR, COMT | ALDH1A1 658/4885HPGD 742/4885TDP1 3131/4885 |
| US-20120264982-A1 | METHOD FOR SEPARATING SALIFIED PHENOLIC COMPOUNDS | COMT, GRHPR, ME1 | ALDH1A1 776/4885HPGD 315/4885TDP1 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.