Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 2/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372954 | 0.88 | SIGMAR1 (0.53) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8091780 | 0.86 | SIGMAR1 (0.53) | MEN1KMT2ASIGMAR1POLB | |
| SCHEMBL8092622 | 0.86 | SIGMAR1 (0.55) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8100063 | 0.86 | BCHE (0.58) | DRD2DRD4DRD3MEN1KMT2A | |
| SCHEMBL8101722 | 0.82 | CALM1 (0.54) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL9378564 | 0.82 | SIGMAR1 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8096264 | 0.82 | SIGMAR1 (0.51) | PLAAT3PLAAT5PLAAT2PLAAT4MEN1 | |
| SCHEMBL8099093 | 0.82 | SIGMAR1 (0.52) | MEN1KMT2ASIGMAR1POLB | |
| SCHEMBL9752778 | 0.82 | MEN1 (0.46) | MEN1KMT2ASIGMAR1POLB | |
| SCHEMBL8093024 | 0.82 | SIGMAR1 (0.51) | MEN1KMT2ASIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | claimed |