Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.43 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.43 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.43 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101722 | 0.91 | CALM1 (0.54) | SIGMAR1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8091780 | 0.89 | SIGMAR1 (0.53) | SIGMAR1POLBMEN1KMT2ACYP3A4 | |
| SCHEMBL9752778 | 0.84 | MEN1 (0.46) | SIGMAR1POLBMEN1KMT2ACYP3A4 | |
| SCHEMBL8093024 | 0.84 | SIGMAR1 (0.51) | SIGMAR1POLBMEN1KMT2ANPC1 | |
| SCHEMBL8099093 | 0.84 | SIGMAR1 (0.52) | SIGMAR1POLBMEN1KMT2ANPC1 | |
| SCHEMBL8096264 | 0.84 | SIGMAR1 (0.51) | SIGMAR1POLBMEN1KMT2ARAB9A | |
| SCHEMBL8092957 | 0.83 | L3MBTL1 (0.56) | SIGMAR1POLBMEN1KMT2A | |
| SCHEMBL8100063 | 0.82 | BCHE (0.58) | SIGMAR1MEN1KMT2A | |
| SCHEMBL9752836 | 0.82 | DRD2 (0.45) | SIGMAR1POLBMEN1KMT2APLAAT3 | |
| SCHEMBL9372954 | 0.82 | SIGMAR1 (0.53) | SIGMAR1POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | claimed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | claimed |
| WO-1991009594-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-07-11 | — | — | WO | claimed |