Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752950 | 0.85 | GABRA5 (0.34) | GABRG2GABRB3GABRA5 | |
| SCHEMBL9752952 | 0.75 | GCGR (0.39) | TGFBR1TGFBR2CSNK1D | |
| SCHEMBL6958480 | 0.68 | GCGR (0.61) | — | |
| SCHEMBL9753119 | 0.67 | PTGS2 (0.36) | — | |
| SCHEMBL9753357 | 0.66 | PTGER1 (0.36) | MAPK14CSNK1D | |
| SCHEMBL5461774 | 0.65 | RORC (0.40) | L3MBTL1TGFBR1TGFBR2MAPK14GRIN2B | |
| SCHEMBL9752951 | 0.64 | LMNA (0.36) | MAPK14CSNK1DGABRA5 | |
| SCHEMBL9753463 | 0.64 | PTGS2 (0.34) | MAPK14 | |
| SCHEMBL9753466 | 0.64 | PTGS2 (0.34) | MAPK14 | |
| SCHEMBL9753771 | 0.63 | GCGR (0.40) | TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |