SCHEMBL973713

SCHEMBL973713

CCCn1c2c[c]ccc2c2cc[c]cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.37
ALDH1A1 P00352 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HTT P42858 1/20 0.37
GFER P55789 1/20 0.37
POLB P06746 2/20 0.33
USP2 O75604 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CNR2 P34972 1/20 0.32
PGR P06401 2/20 0.32
RORA P35398 1/20 0.32
RORC P51449 1/20 0.32
RORB Q92753 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975310 0.89 PGR (0.44) HPGDALDH1A1LMNAKDM4ETSHR
SCHEMBL6420678 0.85 PSEN1 (0.43) CNR2PGRRORARORCRORB
SCHEMBL6423058 0.85 PSEN1 (0.43) CNR2PGRRORARORCRORB
SCHEMBL973904 0.84 HPGD (0.40) HPGDALDH1A1LMNAMAPTKDM4E
SCHEMBL5079006 0.84 KDM4E (0.46) HPGDALDH1A1LMNAMAPTKDM4E
SCHEMBL976299 0.83 ALDH1A1 (0.39) HPGDALDH1A1LMNAMAPTKDM4E
SCHEMBL19179335 0.80 PGR (0.51) MAPTKDM4ECNR2PGRRORA
SCHEMBL975434 0.76 GPR3 (0.44) HPGDALDH1A1MAPTKDM4EHTT
SCHEMBL9776455 0.76 ALDH1A1 (0.55) HPGDALDH1A1LMNAMAPTKDM4E
SCHEMBL974629 0.73 PGR (0.44) HPGDALDH1A1LMNAKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed