Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9776455 | 0.91 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL973713 | 0.83 | HPGD (0.37) | ALDH1A1KDM4EMAPTHTTHPGD | |
| SCHEMBL975523 | 0.83 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL975310 | 0.80 | PGR (0.44) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL334753 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL6420677 | 0.77 | PSEN1 (0.43) | — | |
| SCHEMBL6423058 | 0.77 | PSEN1 (0.43) | — | |
| SCHEMBL6420678 | 0.77 | PSEN1 (0.43) | — | |
| SCHEMBL975434 | 0.75 | GPR3 (0.44) | ALDH1A1KDM4EMAPTHSD17B10HTT | |
| SCHEMBL5160261 | 0.74 | CYP3A4 (0.35) | ALDH1A1KDM4EMAPTHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475937-B2 | Silicone composition and organic light-emitting diode | DOW CORNING CORPORATION (US) | 2013-07-02 | — | — | US | disclosed |
| EP-2262861-B1 | SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE | DOW CORNING (US) | 2012-09-19 | — | — | EP | disclosed |
| US-20110017986-A1 | Silicone Composition and Organic Light-Emitting Diode | DOW CORNING CORPORATION | 2011-01-27 | — | — | US | disclosed |
| EP-2262861-A1 | SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE | Dow Corning Corporation (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009120434-A1 | SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE | DOW CORNING CORPORATION (US) | 2009-10-01 | — | — | WO | disclosed |